Cardiopulmonary bypass increases plasma bradykinin concentrations

Cugno,  M.; Nussberger,  J.; Biglioli,  P.; Giovagnoni,  M. G.; Gardinali,  M.; Agostoni,  A.

doi:10.1016/S0162-3109(99)00072-7

Cardiopulmonary bypass increases plasma bradykinin concentrations

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Serval ID

serval:BIB_770701E14AB7

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

Cardiopulmonary bypass increases plasma bradykinin concentrations

Journal

Immunopharmacology

Author(s)

Cugno M., Nussberger J., Biglioli P., Giovagnoni M. G., Gardinali M., Agostoni A.

ISSN

0162-3109 (Print)

Publication state

Published

Issued date

09/1999

Volume

Number

2-3

Pages

145-7

Notes

Journal Article --- Old month value: Sep

Abstract

An increase of bradykinin (BK) plasma levels together with the activation coagulation cascade, fibrinolysis, complement and cytokines was observed during cardiopulmonary bypass (CPB). Since the procedure of extracorporeal circulation completely excludes the lung, the major site of BK catabolism, our data suggest that a reduced catabolism could contribute to the increase of BK during CPB.

Keywords

Blood Pressure Bradykinin/*blood *Cardiopulmonary Bypass Humans Kininogen, High-Molecular-Weight/blood

OAI-PMH

oai:serval.unil.ch:BIB_770701E14AB7

DOI

10.1016/S0162-3109(99)00072-7

Pubmed

10596846

Web of science

000083847900010

Create date

05/03/2008 17:40