Pharmaceutical interventions on hospital discharge prescriptions: Prospective observational study highlighting challenges for community pharmacists.

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State: Public
Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_76F130D760EB
Type
Article: article from journal or magazin.
Collection
Publications
Title
Pharmaceutical interventions on hospital discharge prescriptions: Prospective observational study highlighting challenges for community pharmacists.
Journal
Drugs Real World Outcomes
Author(s)
Grandchamp S., Blanc A.L., Roussel M., Tagan D., Sautebin A., Dobrinas-Bonazzi M. (co-last), Widmer N. (co-last)
ISSN
2199-1154 (Print)
ISSN-L
2198-9788
Publication state
Published
Issued date
2022
Peer-reviewed
Oui
Volume
9
Number
2
Pages
253-261
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Background: Transition between hospital and ambulatory care is a delicate step involving several healthcare professionals and presenting a considerable risk of drug-related problems.
Objective: To investigate pharmaceutical interventions made on hospital discharge prescriptions by community pharmacists.
Method: This observational, prospective study took place in 14 community pharmacies around a Swiss acute care hospital. We recruited patients with discharge prescriptions (minimum three drugs) from the internal medicine ward of the hospital. The main outcome measures were: number and type of pharmaceutical interventions made by community pharmacists, time spent on discharge prescriptions, number of medication changes during the transition of care.
Results: The study included 64 patients discharged from the hospital. Community pharmacists made a total of 439 interventions; a mean of 6.9 ± 3.5 (range 1-16) interventions per patient. All of the discharge prescriptions required pharmaceutical intervention, and 61 (95%) necessitated a telephone call to the patients' hospital physician for clarifications. The most frequent interventions were: confirming voluntary omission of a drug (31.7%), treatment substitution (20.5%), dose adjustment (16.9%), and substitution for reimbursement issues (8.8%). Roughly half (52%) of all discharge prescriptions required 10-20 min for pharmaceutical validation. The mean number of medication changes per patient was 16.4: 9.6 changes between hospital admission and discharge, 2.6 between hospital discharge and community pharmacy, and 4.2 between community pharmacy and a general practitioner's appointment.
Conclusion: Hospital discharge prescriptions are complex and present a significant risk of medication errors. Community pharmacists play a key role in preventing and identifying drug-related problems.
Pubmed
Web of science
Open Access
Yes
Create date
18/01/2022 15:57
Last modification date
11/08/2022 23:26
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