Isavuconazole for the Treatment of Fungal Infections: A Real-life Experience From the Fungal Infection Network of Switzerland (FUNGINOS).

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State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_7689B1E13106
Type
Article: article from journal or magazin.
Collection
Publications
Institution
UNIL/CHUV
Title
Isavuconazole for the Treatment of Fungal Infections: A Real-life Experience From the Fungal Infection Network of Switzerland (FUNGINOS).
Journal
Open forum infectious diseases
Author(s)
Couchepin J., Reinhold I., Kronig I., Guidi M., Buclin T., Schreiber P.W., Neofytos D., Lamoth F.
Working group(s)
Fungal Infection Network of Switzerland (FUNGINOS)
Contributor(s)
Albrich W., Berezowska S., Berger C., Bergeron A., Bochud P.Y., Boggian K., Conen A., Emonet S., Erard V., Garzoni C., Goldenberger D., Hinic V., Hirzel C., Khanna N., Kohns M., Kronenberg A., Lamoth F., Landis B., Marchetti O., Mühlethaler K., Müller L., Neofytos D., Osthoff M., Pagani J.L., Quiblier C., Reinhold I., Riat A., Rupp N., Sanglard D., Schreiber P.W., Siegemund M., Walti L.
ISSN
2328-8957 (Print)
ISSN-L
2328-8957
Publication state
Published
Issued date
05/2024
Peer-reviewed
Oui
Editor
Albrich W Berezowska S. Berger C. Bergeron A. Bochud P. Y. Boggian K. Conen A. Emonet S. Erard V. Garzoni C. Goldenberger D. Hinic V. Hirzel C. Khanna N. Kohns M. Kronenberg A. Lamoth F. Landis B. Marchetti O. Muhlethaler K. Muller L. Neofytos D. Osthoff M. Pagani J. L. Quiblier C. Reinhold I. Riat A. Rupp N. Sanglard D. Schreiber P. W. Siegemund M. Walti L., Fungal Infection Network of Switzerland
Volume
11
Number
5
Pages
ofae223
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
This analysis of 116 isavuconazole therapy courses shows that hepatic test disturbances (HTDs) were relatively frequent (29% of cases) but rarely led to treatment interruption (5%). Importantly, patients with baseline HTDs, including those attributed to a first-line triazole, did not exhibit a higher risk of subsequent HTD under isavuconazole therapy.
Keywords
aspergillosis, hepatotoxicity, liver, mucormycosis, triazoles
URN
urn:nbn:ch:serval-BIB_7689B1E131066
OAI-PMH
oai:serval.unil.ch:BIB_7689B1E13106
DOI
10.1093/ofid/ofae223
Pubmed
38756765
Web of science
001224188900002
Open Access
Yes
Create date
21/05/2024 14:31
Last modification date
26/07/2024 7:02
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