Meningitis due to non-steroidal anti-inflammatory drugs: an often-overlooked complication of a widely used medication.

Details

Ressource 1Download: 31704799_BIB_7686D251070A.pdf (174.84 [Ko])
State: Public
Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_7686D251070A
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Meningitis due to non-steroidal anti-inflammatory drugs: an often-overlooked complication of a widely used medication.
Journal
BMJ case reports
Author(s)
Desgranges F., Tebib N., Lamy O., Kritikos A.
ISSN
1757-790X (Electronic)
ISSN-L
1757-790X
Publication state
Published
Issued date
07/11/2019
Peer-reviewed
Oui
Volume
12
Number
11
Language
english
Notes
Publication types: Case Reports
Publication Status: epublish
Abstract
A 40-year-old man developed aseptic meningitis after ibuprofen consumption for tension-type headaches. After a thorough diagnostic workup and lack of improvement on empirical therapy for common aetiologies of meningitis (bacterial and viral infections), we suspected non-steroidal anti-inflammatory drug (NSAID) induced meningitis due to the temporal relationship between drug administration and symptom onset. Two days after NSAID suppression, the evolution was progressively favourable with complete resolution of fever and symptoms. On follow-up, symptoms did not recur and there was no neurological sequela. This article summarises the clinical picture and the complementary exams that led to the difficult-to-make diagnosis of NSAID-induced acute meningitis, in parallel with a brief review of the literature.
Keywords
Adult, Anti-Inflammatory Agents, Non-Steroidal/adverse effects, Diagnosis, Differential, Humans, Ibuprofen/adverse effects, Male, Meningitis, Aseptic/chemically induced, contraindications and precautions, headache (including migraines), meningitis
Pubmed
Open Access
Yes
Create date
14/11/2019 12:02
Last modification date
15/01/2021 8:10
Usage data