Use of forensic investigations in anti-doping.
Details
Serval ID
serval:BIB_76289CFB1075
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Use of forensic investigations in anti-doping.
Journal
Forensic Science International
ISSN
1872-6283 (Electronic)
ISSN-L
0379-0738
Publication state
Published
Issued date
2011
Peer-reviewed
Oui
Volume
213
Number
1-3
Pages
109-113
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The fight against doping is mainly focused on direct detection, using analytical methods for the detection of doping agents in biological samples. However, the World Anti-Doping Code also defines doping as possession, administration or attempted administration of prohibited substances or methods, trafficking or attempted trafficking in any prohibited substance or methods. As these issues correspond to criminal investigation, a forensic approach can help assessing potential violation of these rules. In the context of a rowing competition, genetic analyses were conducted on biological samples collected in infusion apparatus, bags and tubing in order to obtain DNA profiles. As no database of athletes' DNA profiles was available, the use of information from the location detection as well as contextual information were key to determine a population of suspected athletes and to obtain reference DNA profiles for comparison. Analysis of samples from infusion systems provided 8 different DNA profiles. The comparison between these profiles and 8 reference profiles from suspected athletes could not be distinguished. This case-study is one of the first where a forensic approach was applied for anti-doping purposes. Based on this investigation, the International Rowing Federation authorities decided to ban not only the incriminated athletes, but also the coaches and officials for 2 years.
Keywords
DNA Fingerprinting, Doping in Sports, Female, Humans, Infusions, Intravenous/instrumentation, Likelihood Functions, Male, Microsatellite Repeats, Needles, Polymerase Chain Reaction, Substance Abuse Detection, Syringes
Pubmed
Web of science
Create date
23/02/2012 17:03
Last modification date
20/08/2019 15:33