Histoplasmose disseminee a Histoplasma capsulatum chez un patient presentant un syndrome d'immunodeficience acquise (SIDA). [Disseminated histoplasmosis due to Histoplasma capsulatum in a patient with acquired immunodeficiency syndrome (AIDS)]

Details

Serval ID
serval:BIB_753BFAE1140C
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Histoplasmose disseminee a Histoplasma capsulatum chez un patient presentant un syndrome d'immunodeficience acquise (SIDA). [Disseminated histoplasmosis due to Histoplasma capsulatum in a patient with acquired immunodeficiency syndrome (AIDS)]
Journal
Schweizerische Medizinische Wochenschrift
Author(s)
Dietrich  P. Y., Bille  J., Fontolliet  C., Regamey  C.
ISSN
0036-7672
Publication state
Published
Issued date
08/1987
Peer-reviewed
Oui
Volume
117
Number
35
Pages
1289-96
Notes
Case Reports
English Abstract
Journal Article
Review --- Old month value: Aug 29
Abstract
Very commonly encountered in the United States, histoplasmosis is rare in Europe, where only 27 patients have so far been infected by this mycosis. In Africa, two varieties of histoplasmosis have been observed: those due to H. capsulatum and H. duboisii. Histoplasmosis due to H. capsulatum is one of the twelve secondary infectious diseases listed in the surveillance definitions of AIDS. This complication has been described only in approximately 20 patients with AIDS; all patients had stayed on the American Continents. We report the case of a 30-year-old African male who lived in Switzerland and in Zaire. With AIDS and multiple Kaposi's sarcoma, the patient died from disseminated histoplasmosis due to H. capsulatum; a peripheral blood smear obtained a few hours before death revealed numerous typical yeast forms of H. capsulatum inside polymorphonuclear leukocytes. Post-mortem examination and cultures confirmed the diagnosis of disseminated histoplasmosis. Histoplasmosis should be suspected in AIDS patients even in Europe, especially where they have stayed in endemic areas. Examination of blood smears and bonemarrow aspirate may allow early recognition of the disease and permit appropriate treatment with amphotericin B and ketoconazole.
Keywords
Acquired Immunodeficiency Syndrome/*complications/epidemiology Female Histoplasma/isolation & purification Histoplasmosis/*complications/epidemiology/microbiology Humans Male Middle Aged Sarcoma, Kaposi/complications United States
Pubmed
Web of science
Create date
11/02/2008 13:39
Last modification date
20/08/2019 15:32
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