Salt subtraction in patients on maintenance hemodialysis. Efficacy and limitations.

Details

Serval ID
serval:BIB_75155A91BA46
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Salt subtraction in patients on maintenance hemodialysis. Efficacy and limitations.
Journal
American Journal of Nephrology
Author(s)
Fasanella d'Amore T., Wauters J.P., Waeber B., Brunner H.R.
ISSN
0250-8095
Publication state
Published
Issued date
1985
Peer-reviewed
Oui
Volume
5
Number
4
Pages
275-281
Language
english
Abstract
In 6 hypertensive patients with terminal renal failure maintained on hemodialysis, the effects of 'salt subtraction' and of sequential ultrafiltrating were evaluated. Following each of 3 weekly hemodialysis sessions, salt subtraction was carried out by ultrafiltrating 1 liter and simultaneously infusing an equal volume of 5% dextrose. This resulted in a net sodium loss without hypovolemia. After a 2-week period of this procedure, the blood pressure prior to dialysis was lower (156/76 +/- 12/5 mm Hg) than after a comparable number of sequential ultrafiltration sessions (181/88 +/- 10/6 mm Hg; mean +/- SEM). This difference was not statistically significant. At the same time, body weight was comparable at 64.4 +/- 3 and 64.7 +/- 4 kg, respectively. Neither plasma renin activity nor plasma catecholamines responded with a clear increase to either procedure. The limited effect on blood pressure and the renin system of a marked sodium removal during salt subtraction suggests that sodium must still be present in excess in these patients. The procedure of salt subtraction appears safe and subjectively well tolerated, but it can probably not be used as the sole means of decreasing total body sodium without associating dietary measures to reduce sodium intake.
Keywords
Adult, Aged, Blood, Blood Pressure, Diet, Sodium-Restricted, Female, Humans, Hypertension, Renal, Kidney Failure, Chronic, Male, Middle Aged, Renal Dialysis, Sodium, Ultrafiltration
Pubmed
Create date
04/03/2009 16:04
Last modification date
20/08/2019 15:32
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