Impact of alcohol consumption on the risk of developing bladder cancer: a systematic review and meta-analysis.

Details

Serval ID
serval:BIB_74E816F6FD49
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Impact of alcohol consumption on the risk of developing bladder cancer: a systematic review and meta-analysis.
Journal
World journal of urology
Author(s)
Vartolomei M.D., Iwata T., Roth B., Kimura S., Mathieu R., Ferro M., Shariat S.F., Seitz C.
ISSN
1433-8726 (Electronic)
ISSN-L
0724-4983
Publication state
Published
Issued date
11/2019
Peer-reviewed
Oui
Volume
37
Number
11
Pages
2313-2324
Language
english
Notes
Publication types: Journal Article ; Meta-Analysis ; Systematic Review
Publication Status: ppublish
Abstract
Epidemiologic studies that investigated alcohol consumption in relation to the risk of bladder cancer (BCa) have demonstrated inconsistent results. We conducted a systematic review and meta-analysis of the literature to investigate the association of alcohol including different types of alcoholic beverages consumption with the risk of BCa.
A systematic search of Web of Science, Medline/PubMed and Cochrane library was performed in May 2018. Studies were considered eligible if they assessed the risk of BCa due to alcohol consumption (moderate or heavy dose) and different types of alcoholic beverages (moderate or heavy dose) in multivariable analysis in the general population (all genders, males or females) or compared with a control group of individuals without BCa.
observational cohorts or case-control.
Sixteen studies were included in this meta-analysis. Moderate and heavy alcohol consumption did not increase the risk of BCa in the entire population. Sub-group and sensitivity analyses revealed that heavy alcohol consumption increased significantly the risk of BCa in the Japanese population, RR 1.31 (95% CI 1.08-1.58, P < 0.01) in the multivariable analysis, and in males RR of 1.50 (95% CI 1.18-1.92, P < 0.01), with no significant statistical heterogeneity. Moreover, heavy consumption of spirits drinks increased the risk of BCa in males, RR 1.42 (95% CI 1.15-1.75, P < 0.01).
In this meta-analysis, moderate and heavy alcohol consumption did not increase the risk of bladder cancer significantly. However, heavy consumption of alcohol might increase the risk of BCa in males and in some specific populations.
Keywords
Alcohol Drinking/adverse effects, Female, Humans, Male, Risk Assessment, Urinary Bladder Neoplasms/epidemiology, Urinary Bladder Neoplasms/etiology, Alcohol consumption, Bladder cancer, Cancer risk
Pubmed
Web of science
Create date
08/01/2021 20:22
Last modification date
09/01/2021 7:26
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