Candidoses du sujet non neutropénique: de la colonisation à l'infection [Candidiasis among non-neutropenic patients: from colonization to infection]
Details
Serval ID
serval:BIB_74D24CE169D1
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Candidoses du sujet non neutropénique: de la colonisation à l'infection [Candidiasis among non-neutropenic patients: from colonization to infection]
Journal
Annales Françaises d'Anesthésie et de Réanimation
ISSN
0750-7658
Publication state
Published
Issued date
04/2001
Peer-reviewed
Oui
Volume
20
Number
4
Pages
382-388
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review
Abstract
Invasive candidiasis is a dread complication in hospitalized patients, characterized by a mortality comparable to that of septic shock (40% to 60%). Its incidence in hospitalized patients is 0.5/1000 admissions, but it complicates about 10 per 1,000 admissions in critical care where it represents 10% to 15% of all nosocomial infections. Although a high proportion of hospitalized patients may become colonized with Candida spp, the clinical signs of infection manifest only late, rending it difficult to diagnose. A better knowledge of their pathophysiology and the availability of triazoles compounds, less toxic than amphotericin B, allowed the concept of early empirical or preemptive treatment. These strategies are based on the prompt identification of risk factors and require continuous attention from skilled physicians. However, the prescription of triazoles has to be restricted to carefully selected groups of patients to avoid the emergence and the dissemination of resistant strains.
Keywords
Candidiasis/epidemiology, Candidiasis/microbiology, Cross Infection/epidemiology, Cross Infection/microbiology, Hospitalization, Humans, Risk Factors
Pubmed
Web of science
Create date
24/01/2008 17:57
Last modification date
20/08/2019 15:32