La polychondrite chronique atrophiante [Relapsing polychondritis]

Details

Serval ID
serval:BIB_7472B76077EF
Type
Article: article from journal or magazin.
Collection
Publications
Title
La polychondrite chronique atrophiante [Relapsing polychondritis]
Journal
Revue medicale suisse
Author(s)
Arlettaz L., Ribi C.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
21/04/2010
Peer-reviewed
Oui
Volume
6
Number
245
Pages
830-834
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
Relapsing polychondritis is a rare systemic disease. Clinical manifestations are variable and the condition is frequently associated with other diseases. Chondritis typically involves ears, nose, costal cartilages and upper airways. Other classical features include scleritis and episcleritis, mucocutaneous lesions, arthralgia and constitutional symptoms. Repeated inflammation of cartilaginous structures may lead to deformities of the ears, the nose and the airways. Tracheobronchomalacia and aortitis of the ascending portion resulting in aortic regurgitation or aneurysm are feared complications. Treatment is mainly based on systemic corticosteroids alone or in association with immunosuppressants. Several biological immunosuppressive agents are reported effective in refractory disease.
Keywords
Adrenal Cortex Hormones/therapeutic use, Aneurysm/etiology, Anti-Inflammatory Agents, Non-Steroidal/therapeutic use, Aortic Valve Insufficiency/etiology, Aortitis/etiology, Diagnosis, Differential, Drug Therapy, Combination, Ear, External/pathology, Humans, Immunosuppressive Agents/therapeutic use, Laryngeal Diseases/etiology, Nose/pathology, Polychondritis, Relapsing/complications, Polychondritis, Relapsing/drug therapy, Polychondritis, Relapsing/pathology, Polychondritis, Relapsing/prevention & control, Scleritis/etiology, Skin/pathology, Tracheal Diseases/etiology, Tracheobronchomalacia/etiology, Tracheobronchomalacia/pathology, Treatment Outcome
Pubmed
Create date
01/07/2020 12:34
Last modification date
02/07/2020 9:36
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