New Horizons for Dissecting Epistasis in Crop Quantitative Trait Variation.

Details

Serval ID
serval:BIB_737563E17177
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
New Horizons for Dissecting Epistasis in Crop Quantitative Trait Variation.
Journal
Annual review of genetics
Author(s)
Soyk S., Benoit M., Lippman Z.B.
ISSN
1545-2948 (Electronic)
ISSN-L
0066-4197
Publication state
Published
Issued date
23/11/2020
Peer-reviewed
Oui
Volume
54
Pages
287-307
Language
english
Notes
Publication types: Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Uncovering the genes, variants, and interactions underlying crop diversity is a frontier in plant genetics. Phenotypic variation often does not reflect the cumulative effect of individual gene mutations. This deviation is due to epistasis, in which interactions between alleles are often unpredictable and quantitative in effect. Recent advances in genomics and genome-editing technologies are elevating the study of epistasis in crops. Using the traits and developmental pathways that were major targets in domestication and breeding, we highlight how epistasis is central in guiding the behavior of the genetic variation that shapes quantitative trait variation. We outline new strategies that illuminate how quantitative epistasis from modified gene dosage defines background dependencies. Advancing our understanding of epistasis in crops can reveal new principles and approaches to engineering targeted improvements in agriculture.
Keywords
cis-regulatory, crop domestication and improvement, epistasis, gene dosage, genome editing, quantitative variation
Pubmed
Web of science
Create date
09/09/2020 8:16
Last modification date
23/12/2020 6:24
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