Vascular mechanisms in the developmental programming of cardio-vascular disease.

Details

Serval ID
serval:BIB_73534C430BB7
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Vascular mechanisms in the developmental programming of cardio-vascular disease.
Journal
La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
Author(s)
Tauzin L., Risso F., Buffat C., Serra G., Simeoni U.
ISSN
0391-5387 (Print)
ISSN-L
0391-5387
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
27
Number
5
Pages
18-23
Language
english
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Abstract
Several studies suggest that adverse events during foetal life can program cardiovascular diseases in adulthood. Barker et al. identified a relationship between low birth weight and an increased risk of arterial hypertension, carotid arteriosclerosis, and mortality by coronary heart disease or stroke in adulthood. These findings led to the "foetal origins" hypothesis, which is that cardiovascular disease originates in the adaptations to an adverse intrauterine environment. Such adaptations may permanently alter the cardiovascular structure and physiology through the process of programming. Several factors, such as impaired foetal growth, premature birth or postnatal growth of low birth weight infants may be involved, but to which extent is still unclear.
Keywords
Arteries/pathology, Arteries/physiopathology, Cardiovascular Diseases/embryology, Elastin/physiology, Fetal Development, Humans, Infant, Newborn, Infant, Premature
Pubmed
Create date
22/02/2015 11:54
Last modification date
20/08/2019 14:31
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