Five year impact of chemotherapy on morbidity attributable to Schistosoma japonicum infection in the Dongting Lake region.

Details

Serval ID
serval:BIB_7320
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Five year impact of chemotherapy on morbidity attributable to Schistosoma japonicum infection in the Dongting Lake region.
Journal
Tropical Medicine and International Health
Author(s)
Ross A.G., Li Y., Booth M., Sleigh A.C., Williams G.M., McManus D.P.
ISSN
1360-2276
Publication state
Published
Issued date
1998
Volume
3
Number
10
Pages
837-841
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
Abstract
OBJECTIVE: To determine changes in the last 5 years of the fraction of acute and chronic symptoms attributable to schistosomiasis japonica in fishing communities with moderate endemicity in the Dongting Lake region of China. METHOD: Complete medical histories, physical examinations, and stool samples were obtained from 1909 individuals (53% male) ranging in age from 4 to 81 years. Age, sex, occupation, frequency of water contact, number of times treated for schistosomiasis, and last year of treatment were tested as potential effect modifiers and confounders. RESULTS: Overall, there were very few infected cases and very little variation in any prevalence ratio with infection intensity, sex, age, year of last treatment, number of times treated or frequency of water contact. The attributable fraction of liver enlargement in one village was estimated at 0.114 (11.4%), although this was not significantly > 0(95% CI; -0.008-0.237). CONCLUSION: The chemotherapy-based schistosomiasis control programme in this locality has succeeded in reducing attributable morbidity to undetectable levels, but many uncertainties remain about sustaining control efforts in the future. Both old and new control strategies will have to be examined if the health and well-being of these people are to be maintained into the next millennium, given that periodic chemotherapy will not be accepted indefinitely.
Keywords
Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, China/epidemiology, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prevalence, Schistosomiasis japonica/drug therapy, Schistosomiasis japonica/epidemiology
Pubmed
Web of science
Create date
19/11/2007 12:45
Last modification date
20/08/2019 14:31
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