Carpal tunnel syndrome in 100 patients: sensitivity, specificity of multi-neurophysiological procedures and estimation of axonal loss of motor, sensory and sympathetic median nerve fibers

Details

Serval ID
serval:BIB_728645F03F14
Type
Article: article from journal or magazin.
Collection
Publications
Title
Carpal tunnel syndrome in 100 patients: sensitivity, specificity of multi-neurophysiological procedures and estimation of axonal loss of motor, sensory and sympathetic median nerve fibers
Journal
Journal of the Neurological Sciences
Author(s)
Kuntzer  T.
ISSN
0022-510X (Print)
Publication state
Published
Issued date
12/1994
Peer-reviewed
Oui
Volume
127
Number
2
Pages
221-9
Notes
Clinical Trial Journal Article --- Old month value: Dec 20
Abstract
This prospective study meets all six criteria recently recommended by a quality assurance committee of the AAEM and defines criteria of abnormality, sensitivity and specificity of 19 sensorimotor and sympathetic parameters in 100 patients who were suspected on clinical grounds of having carpal tunnel syndrome (CTS), and in 70 control subjects. Nine parameters reached a specificity of 97%, permitting the electrodiagnosis of CTS in 87% of the patients studied. The results in this study confirm that median sensory nerve conduction studies are more frequently abnormal than are studies of motor nerve conduction. The so far unknown usefulness of parameters such as median F-wave abnormalities and residual latency, terminal latency index and sensory nerve action potential (SNAP) amplitude was assessed; these parameters were not found sensitive enough, yet high specific (SNAP amplitude) or high sensitive yet low specific (F-wave abnormalities, residual latency and terminal latency index) and are therefore of little value in the early clinical electrodiagnostic evaluation of patients with CTS. Finally, in the patients studied, some degree of axonal loss for motor, sensory and sympathetic median nerve fibers was found in 42% of cases and 6 patients had a double-crush syndrome and 6 others had a concomitant ulnar neuropathy at the elbow.
Keywords
Action Potentials/physiology Adrenergic Fibers/*physiology Adult Aged Aged, 80 and over Axons/*physiology Carpal Tunnel Syndrome/*pathology/physiopathology Electromyography Female Hand/innervation/physiopathology Humans Male Median Nerve/*pathology/physiopathology Middle Aged Motor Neurons/*physiology Neural Conduction/physiology Neurologic Examination Neurons, Afferent/*physiology Prospective Studies
Pubmed
Web of science
Create date
25/01/2008 13:43
Last modification date
03/03/2018 18:17
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