Efficacy of two silicone-hydrogel contact lenses for bandage use after photorefractive keratectomy.

Details

Serval ID
serval:BIB_71C5B5ADED98
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Efficacy of two silicone-hydrogel contact lenses for bandage use after photorefractive keratectomy.
Journal
Contact lens & anterior eye
Author(s)
Plaka A., Grentzelos M.A., Astyrakakis N.I., Kymionis G.D., Pallikaris I.G., Plainis S.
ISSN
1476-5411 (Electronic)
ISSN-L
1367-0484
Publication state
Published
Issued date
10/2013
Peer-reviewed
Oui
Volume
36
Number
5
Pages
243-246
Language
english
Notes
Publication types: Controlled Clinical Trial ; Journal Article
Publication Status: ppublish
Abstract
To evaluate the efficacy of two silicone hydrogel (SiH) contact lenses, approved for continuous wear for one week, following photorefractive keratectomy (PRK).
Forty seven myopic patients (94 eyes) undergone bilateral PRK were enrolled in this prospective, double-masked, comparative study. One eye of each patient was fitted with a Lotrafilcon B lens (Ciba Vision, Duluth, US; 30-day recommended replacement) whereas the fellow eye was fitted with an Asmofilcon A lens (Menicon, Nagoya, Japan; 14-day recommended replacement). Epithelial defect size was assessed using slit lamp biomicroscopy on the day of surgery and at days 1-4 post-operatively. Uncorrected and best-corrected visual acuity and retinal straylight (C-Quant, Oculus Optigerate, Germany) were evaluated pre-operatively and one month post-operatively.
Average epithelial defect size for Asmofilcon A and Lotrafilcon B was 25.5±11.0mm(2) vs. 27.1±9.9mm(2) at day 1 (p=0.007) and 6.3±7.0mm(2) vs. 9.2±9.5mm(2) at day 2 (p=0.012) post-operatively. Re-epithelialization at day 3 was completed in 87.2% of the eyes fitted with Asmofilcon A lenses, compared to 74.5% with Lotrafilcon B lenses (p=0.012). At the 3rd post-operative day 29.8% of re-epithelialized eyes showed irregular suture with Lotrafilcon B, compared to 12.8% eyes with Asmofilcon A lenses (p<0.001). Finally, no statistically significant differences were found post-operatively between the two lenses retinal straylight (p=0.98) and best-corrected visual acuity (p=0.68).
SiH lenses can be used as an effective bandage after PRK due to the limited time requested for achieving complete corneal re-epithelialization. Faster and smoother epithelial healing is provided with Asmofilcon A over Lotrafilcon B lenses.
Keywords
Adult, Bandages, Combined Modality Therapy/instrumentation, Combined Modality Therapy/methods, Contact Lenses, Hydrophilic, Double-Blind Method, Female, Humans, Hydrogels, Male, Middle Aged, Myopia/diagnosis, Myopia/therapy, Photorefractive Keratectomy/instrumentation, Photorefractive Keratectomy/methods, Recovery of Function, Silicones, Treatment Outcome, Young Adult, Bandage, Contact lens, Epithelial healing, PRK, Silicone-hydrogel
Pubmed
Web of science
Create date
01/10/2019 13:04
Last modification date
06/10/2019 5:26
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