Management of thyroid cytological material, preanalytical procedures and bio-banking.

Details

Serval ID
serval:BIB_70866FBE887E
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Management of thyroid cytological material, preanalytical procedures and bio-banking.
Journal
Cytopathology
Author(s)
Bode-Lesniewska B., Cochand-Priollet B., Straccia P., Fadda G., Bongiovanni M.
ISSN
1365-2303 (Electronic)
ISSN-L
0956-5507
Publication state
Published
Issued date
01/2019
Peer-reviewed
Oui
Volume
30
Number
1
Pages
7-16
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Thyroid nodules are common and are increasingly detected due to recent advances in imaging techniques. However, clinically relevant thyroid cancer is rare and the mortality from aggressive thyroid cancer remains constant. Fine needle aspiration cytology (FNAC) is a standard method for diagnosing thyroid malignancy and the discrimination of malignant nodules from goitre. As the examined nodules on thyroid FNAC are often small incidental findings, it is important to maintain a low rate of undetermined diagnoses requiring further clinical work up or surgery. The most important factors determining the accuracy of the cytological diagnosis and suitability for biobanking of thyroid FNACs are the quality of the sample and availability of adequate tissue for auxiliary studies. This article discusses technical aspects (preanalytics) of performing thyroid FNAC, including image guidance and rapid on-site evaluation, sample collection methods (conventional slides, liquid-based methods, cell blocks) and storage (bio-banking). The spectrum of special studies (immunocytochemistry on direct slides or liquid-based cytology, immunohistochemistry on cell blocks and molecular methods) required for improving the precision of the cytological diagnosis of the thyroid nodules is also discussed.
Keywords
FNAC, biobanking, pre-analytical procedures, thyroid, fine needle aspiration cytology, preanalytical procedures
Pubmed
Web of science
Open Access
Yes
Create date
14/06/2018 16:11
Last modification date
20/08/2019 14:29
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