An epidemic of food-borne listeriosis in western Switzerland: description of 57 cases involving adults

Details

Ressource 1Download: serval:BIB_706F1A41901D.P001 (591.58 [Ko])
State: Public
Version: author
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_706F1A41901D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
An epidemic of food-borne listeriosis in western Switzerland: description of 57 cases involving adults
Journal
Clinical Infectious Diseases
Author(s)
Bula  C. J., Bille  J., Glauser  M. P.
ISSN
1058-4838 (Print)
Publication state
Published
Issued date
01/1995
Volume
20
Number
1
Pages
66-72
Language
english
Notes
Journal Article --- Old month value: Jan
licence nationale
Abstract
This article describes 57 cases of listeriosis that occurred in adults in western Switzerland during an outbreak associated with the consumption of a soft cheese. Twenty-one percent of the cases were of bacteremia, 40% were of meningitis, and 39% were of meningoencephalitis. Overall, 42% of the patients had an underlying disease and 54% were > 65 years of age. Patients with bacteremia were significantly older than those with meningitis or meningoencephalitis (median ages, 75, 69, and 55 years, respectively). The epidemic strain, defined by phage typing, was isolated in three-quarters of the listerial cases observed during the epidemic period and did not appear to differ significantly from the nonepidemic strains in terms of virulence. The overall mortality associated with the 57 cases was 32%. Among the patients' characteristics, age and type of clinical presentation were independent predictors of death in a multivariate logistic regression model (pseudo-r2 [coefficient of determination], .26; both P values < .05), and a presentation of meningoencephalitis was associated with an increased death risk (odds ratio, 6.5; 95% confidence interval, 1.1-39.5; P < .05). Neurological sequelae developed in 30% of the survivors of CNS listeriosis.
Keywords
Adult Aged Bacteremia/epidemiology/microbiology/mortality Cheese/microbiology *Disease Outbreaks Female Food Poisoning/*epidemiology/microbiology/mortality Humans Listeria/isolation & purification/pathogenicity Listeria Infections/*epidemiology/microbiology/mortality Male Meningitis, Listeria/epidemiology/microbiology/mortality Meningoencephalitis/epidemiology/microbiology/mortality Middle Aged Prognosis Switzerland/epidemiology Virulence
Pubmed
Web of science
Open Access
Yes
Create date
24/01/2008 16:35
Last modification date
01/10/2019 6:18
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