An in-silico analysis of the effect of heart position and orientation on the ECG morphology and vectorcardiogram parameters in patients with heart failure and intraventricular conduction defects.
Details
Serval ID
serval:BIB_706003FCBFB4
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
An in-silico analysis of the effect of heart position and orientation on the ECG morphology and vectorcardiogram parameters in patients with heart failure and intraventricular conduction defects.
Journal
Journal of electrocardiology
ISSN
1532-8430 (Electronic)
ISSN-L
0022-0736
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
48
Number
4
Pages
617-625
Language
english
Notes
Publication types: Comparative Study ; Evaluation Study ; Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
The aim of this study was to investigate the influence of geometrical factors on the ECG morphology and vectorcardiogram (VCG) parameters.
Patient-tailored models based on five heart-failure patients with intraventricular conduction defects (IVCDs) were created. The heart was shifted up to 6 cm to the left, right, up, and down and rotated ±30° around the anteroposterior axis. Precordial electrodes were shifted 3 cm down.
Geometry modifications strongly altered ECG notching/slurring and intrinsicoid deflection time. Maximum VCG parameter changes were small for QRS duration (-6% to +10%) and QRS-T angle (-6% to +3%), but considerable for QRS amplitude (-36% to +59%), QRS area (-37% to +42%), T-wave amplitude (-41% to +36%), and T-wave area (-42% to +33%).
The position of the heart with respect to the electrodes is an important factor determining notching/slurring and voltage-dependent parameters and therefore must be considered for accurate diagnosis of IVCDs.
Patient-tailored models based on five heart-failure patients with intraventricular conduction defects (IVCDs) were created. The heart was shifted up to 6 cm to the left, right, up, and down and rotated ±30° around the anteroposterior axis. Precordial electrodes were shifted 3 cm down.
Geometry modifications strongly altered ECG notching/slurring and intrinsicoid deflection time. Maximum VCG parameter changes were small for QRS duration (-6% to +10%) and QRS-T angle (-6% to +3%), but considerable for QRS amplitude (-36% to +59%), QRS area (-37% to +42%), T-wave amplitude (-41% to +36%), and T-wave area (-42% to +33%).
The position of the heart with respect to the electrodes is an important factor determining notching/slurring and voltage-dependent parameters and therefore must be considered for accurate diagnosis of IVCDs.
Keywords
Aged, Arrhythmias, Cardiac/complications, Arrhythmias, Cardiac/diagnosis, Arrhythmias, Cardiac/physiopathology, Computer Simulation, Diagnosis, Computer-Assisted/methods, Electrocardiography/methods, Female, Heart Conduction System/physiopathology, Heart Failure/complications, Heart Failure/diagnosis, Heart Failure/physiopathology, Humans, Male, Middle Aged, Models, Cardiovascular, Patient Positioning/methods, Patient-Specific Modeling, Posture, Reproducibility of Results, Sensitivity and Specificity, Vectorcardiography/methods, Computer simulation, ECG morphology, Geometry, VCG
Pubmed
Web of science
Create date
15/11/2017 16:50
Last modification date
23/02/2024 14:58
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