Primary Chronic Sclerosing Osteomyelitis: A New Diagnostic Tool.
Details
Serval ID
serval:BIB_7022C3B760F5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Primary Chronic Sclerosing Osteomyelitis: A New Diagnostic Tool.
Journal
Diagnostics
ISSN
2075-4418 (Print)
ISSN-L
2075-4418
Publication state
Published
Issued date
29/11/2023
Peer-reviewed
Oui
Volume
13
Number
23
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Abstract
Primary chronic sclerosing osteomyelitis is a rare and complex pathology and remains a diagnostic and therapeutic challenge. Our aim is to show our experience with a new diagnostic tool.
Four patients aged from 26 to 67 were referred to the department of oral and maxillofacial surgery of University Hospital CHUV in Lausanne between January 2010 and December 2018 for chronic mandibular pain without infectious signs nor symptoms. All patients underwent three-phase bone scintigraphy and anti-granulocyte antibody scintigraphy.
Three-phase bone scintigraphy demonstrated radiotracer uptake at the zone of pain, whereas anti-granulocyte antibody scintigraphy showed no uptake, thus rendering an infectious origin unlikely.
A combination of the two different scintigraphies should be considered in order to guide the clinician in the diagnosis of primary chronic sclerosing osteomyelitis, thus preventing patients from undergoing unnecessary imagery and useless treatment, and also allowing an early diagnosis.
Four patients aged from 26 to 67 were referred to the department of oral and maxillofacial surgery of University Hospital CHUV in Lausanne between January 2010 and December 2018 for chronic mandibular pain without infectious signs nor symptoms. All patients underwent three-phase bone scintigraphy and anti-granulocyte antibody scintigraphy.
Three-phase bone scintigraphy demonstrated radiotracer uptake at the zone of pain, whereas anti-granulocyte antibody scintigraphy showed no uptake, thus rendering an infectious origin unlikely.
A combination of the two different scintigraphies should be considered in order to guide the clinician in the diagnosis of primary chronic sclerosing osteomyelitis, thus preventing patients from undergoing unnecessary imagery and useless treatment, and also allowing an early diagnosis.
Keywords
anti-granulocyte antibody scintigraphy, primary chronic sclerosing osteomyelitis, three-phase bone scintigraphy
Pubmed
Web of science
Open Access
Yes
Create date
15/12/2023 15:29
Last modification date
09/08/2024 16:01