Radiobiology of Radiosurgery for Neurosurgeons.

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State: Public
Version: author
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Serval ID
serval:BIB_6FA59D1FCD35
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Radiobiology of Radiosurgery for Neurosurgeons.
Journal
Neurology India
Author(s)
Tuleasca C., Tripathi M., Starnoni D., Daniel R.T., Reyns N., Levivier M.
ISSN
1998-4022 (Electronic)
ISSN-L
0028-3886
Publication state
Published
Issued date
2023
Peer-reviewed
Oui
Volume
71
Number
Supplement
Pages
S14-S20
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Stereotactic radiosurgery (SRS) is a precise focusing of radiation to a targeted point or larger area of tissue. With advances in technology, the radiobiological understanding of this modality has trailed behind. Although found effective in both short- and long-term follow-up, there are ongoing evolution and controversial topics such as dosing pattern, dose per fraction in hypo-fractionnated regimens, inter-fraction interval, and so on. Radiobiology of radiosurgery is not a mere extension of conventional fractionation radiotherapy, but it demands further evaluation of the dose calculation on the linear linear-quadratic model, which has also its limits, biologically effective dose, and radiosensitivity of the normal and target tissue. Further research is undergoing to understand this somewhat controversial topic of radiosurgery better.
Keywords
Humans, Radiosurgery, Neurosurgeons, Radiobiology, Dose Fractionation, Radiation, BED, Gamma Knife, biologically effective dose, radiobiology, radiosurgery
Pubmed
Web of science
Create date
11/04/2023 17:28
Last modification date
23/07/2024 6:56
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