Hypoxia, energy balance, and obesity: An update.

Details

Ressource 1Request a copy Sous embargo indéterminé.
State: Public
Version: Final published version
License: All rights reserved
Serval ID
serval:BIB_6E8C3B26BCD1
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Hypoxia, energy balance, and obesity: An update.
Journal
Obesity reviews
Author(s)
Kayser B., Verges S.
ISSN
1467-789X (Electronic)
ISSN-L
1467-7881
Publication state
Published
Issued date
20/01/2021
Peer-reviewed
Oui
Pages
e13192
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
Because of the enduring rise in the prevalence of obesity worldwide, there is continued interest in hypoxia as a mechanism underlying the pathophysiology of obesity and its comorbidities and as a potential therapeutic adjunct for the management of the disease. Lifelong exposure to altitude is accompanied by a lower risk for obesity, whereas altitude sojourns are generally associated with a loss of body mass. A negative energy balance upon exposure to hypoxia can be due to a combination of changes in determinants of energy expenditure (resting metabolic rate and physical activity energy expenditure) and energy intake (appetite). Over the past 15 years, the potential therapeutic interest of hypobaric or normobaric hypoxic exposure in individuals with obesity-to lower body mass and improve health status-has become an active field of research. Various protocols have been implemented, using actual altitude sojourns or intermittent normobaric hypoxic exposures, at rest or in association with physical activity. Although several studies suggest benefits on body mass and cardiovascular and metabolic variables, further investigations are required before recommending hypoxic exposure in obesity management programs. Future studies should also better clarify the effects of hypoxia on appetite, the intestinal microbiota, and finally on overall energy balance.
Keywords
energy balance, exercise, hypoxia, obesity
Pubmed
Create date
26/01/2021 13:10
Last modification date
23/02/2021 7:27
Usage data