Neuropeptide Y, somatostatin, and cholecystokinin neurone preservation in anaplastic astrocytomas.

Details

Serval ID
serval:BIB_6E722450B84F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Neuropeptide Y, somatostatin, and cholecystokinin neurone preservation in anaplastic astrocytomas.
Journal
Acta Neuropathologica
Author(s)
Przedborski S., Goldman S., Schiffmann S.N., Vierendeels G., Depierreux M., Levivier M., Hildebrand J., Vanderhaeghen J.J.
ISSN
0001-6322 (Print)
ISSN-L
0001-6322
Publication state
Published
Issued date
1988
Peer-reviewed
Oui
Volume
76
Number
5
Pages
507-510
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Using immunohistochemistry, well-preserved neuronal cell bodies and fibres containing neuropeptide Y, somatostatin, and cholecystokinin immunoreactivity have been identified in all seven supratentorial anaplastic astrocytomas studied. These neurones have been shown not only on the edge but also in the depth of the neoplastic tissue. These neuropeptides were not present in 18 other intracranial tumours (3 astrocytomas, 1 subependymoma, 8 glioblastoma multiformes, 1 meningioma, and 5 metastases). In all 25 intracranial tumours studied, no immunoreactivity was found for vasoactive intestinal polypeptide, substance P, methionine-enkephalin, leucine-enkephalin, synenkephalin, neurophysin I-II, and corticotropin releasing factor.
Keywords
Astrocytoma/analysis, Astrocytoma/pathology, Cholecystokinin/analysis, Humans, Immunohistochemistry, Neuropeptide Y/analysis, Somatostatin/analysis, Supratentorial Neoplasms/analysis, Supratentorial Neoplasms/pathology
Pubmed
Web of science
Create date
20/01/2008 18:35
Last modification date
20/08/2019 15:27
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