Changes in risk factors and preventive treatments by stroke subtypes over 20 years: a population-based study

Details

Ressource 1Request a copy Sous embargo indéterminé.
State: Public
Version: author
License: Not specified
Serval ID
serval:BIB_6DC3470A8538
Type
Article: article from journal or magazin.
Collection
Publications
Title
Changes in risk factors and preventive treatments by stroke subtypes over 20 years: a population-based study
Journal
J Neurol Sci
Author(s)
Bejot Y., Osseby G. V., Gremeaux V., Durier J., Rouaud O., Moreau T., Giroud M.
ISSN
1878-5883 (Electronic)
ISSN-L
0022-510X
Publication state
Published
Issued date
2009
Volume
287
Number
1-2
Pages
84-8
Language
english
Notes
Bejot, Yannick
Osseby, Guy-Victor
Gremeaux, Vincent
Durier, Jerome
Rouaud, Olivier
Moreau, Thibault
Giroud, Maurice
eng
Netherlands
J Neurol Sci. 2009 Dec 15;287(1-2):84-8. doi: 10.1016/j.jns.2009.08.062. Epub 2009 Sep 19.
Abstract
In order to evaluate progress in preventive therapeutic strategies, and to identify potential targets for improvement, it is essential to assess changes in the risk factors and preventive treatment of stroke over time. All of the strokes occurring within the population of Dijon, France (150,000 inhabitants), were prospectively ascertained from 1985 to 2004. Changes in stroke risk factors and preventive medications were analyzed by stroke subtypes. We recorded 725 lacunar infarcts (LI), 497 cardioembolic (CE) strokes, 2054 ischemic stroke from atheroma of large arteries or from other and undetermined causes (OIS), and 341 primary cerebral haemorrhages (PCH). Over the 20years, the prevalence of hypercholesterolemia increased whatever the stroke subtype (p<0.01) whereas that of diabetes only rose in LI and OIS stroke. The proportion of stroke patients on antiplatelet agents increased overall (p<0.01) and the proportion of patients on anticoagulants rose in CE stroke (p=0.01) and PCH (p<0.01). The proportion of patients on antihypertensive treatment only increased in CE stroke (p=0.01). The risk factor profile and the preventive treatments in stroke patients showed divergent variations over the 20years, according to the stroke subtype considered. These modifications certainly reflect changes in the therapeutic strategies for the preventive management of the population at risk.
Keywords
Aged, Anticoagulants/therapeutic use, Antihypertensive Agents/therapeutic use, Brain Infarction/drug therapy/epidemiology/prevention & control, Brain Ischemia/drug therapy/epidemiology/prevention & control, Cerebral Hemorrhage/drug therapy/epidemiology/prevention & control, Cohort Studies, Comorbidity, Diabetes Mellitus/*epidemiology, Female, France/epidemiology, Humans, Hypercholesterolemia/*epidemiology, Hypertension/drug therapy/*epidemiology, Intracranial Embolism/drug therapy/epidemiology/prevention & control, Longitudinal Studies, Male, Platelet Aggregation Inhibitors/therapeutic use, Prospective Studies, Risk Factors, Risk Reduction Behavior, Stroke/classification/*epidemiology/*therapy, Time Factors
Pubmed
Create date
26/11/2019 11:35
Last modification date
06/05/2020 5:26
Usage data