Prophylaxe und Therapie der posttraumatischen Belastungsstörung mit Propranolol : Evidenz und ethische Analyse [Prophylaxis and therapy of post-traumatic stress disorder with propranolol: evidence and ethical analysis]
Details
Serval ID
serval:BIB_6D7D039C7418
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Prophylaxe und Therapie der posttraumatischen Belastungsstörung mit Propranolol : Evidenz und ethische Analyse [Prophylaxis and therapy of post-traumatic stress disorder with propranolol: evidence and ethical analysis]
Journal
Der Nervenarzt
ISSN
1433-0407 (Electronic)
ISSN-L
0028-2804
Publication state
Published
Issued date
10/2013
Peer-reviewed
Oui
Volume
84
Number
10
Pages
1183-1189
Language
german
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
The beta-antagonistic agent propranolol is increasingly being used in clinical trials for the prophylaxis and treatment of post-traumatic stress disorder (PTSD). This article discusses the evidence for the effectiveness of propranolol in the prophylaxis and treatment of PTSD and the ethical implications of research on these treatment approaches. The efficacy of a prophylactic or therapeutic use could not be shown during the last decade. Both treatment approaches raise ethical questions that should already be addressed during the clinical trials.
Keywords
Adrenergic beta-Antagonists/adverse effects, Adrenergic beta-Antagonists/therapeutic use, Animals, Arousal/drug effects, Combined Modality Therapy, Disease Models, Animal, Ethics, Medical, Evidence-Based Medicine/ethics, Humans, Informed Consent, Memory, Episodic, Propranolol/adverse effects, Propranolol/therapeutic use, Psychotherapy, Randomized Controlled Trials as Topic, Risk Assessment, Stress Disorders, Post-Traumatic/drug therapy, Stress Disorders, Post-Traumatic/prevention & control, Stress Disorders, Post-Traumatic/psychology
Pubmed
Web of science
Create date
14/07/2017 10:09
Last modification date
20/08/2019 15:27
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