Impact of Roux-en-Y gastric bypass and sleeve gastrectomy on fetal growth and relationship with maternal nutritional status.

Details

Serval ID
serval:BIB_6D46F032AC68
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Impact of Roux-en-Y gastric bypass and sleeve gastrectomy on fetal growth and relationship with maternal nutritional status.
Journal
Surgery for obesity and related diseases
Author(s)
Coupaye M., Legardeur H., Sami O., Calabrese D., Mandelbrot L., Ledoux S.
ISSN
1878-7533 (Electronic)
ISSN-L
1550-7289
Publication state
Published
Issued date
10/2018
Peer-reviewed
Oui
Volume
14
Number
10
Pages
1488-1494
Language
english
Notes
Publication types: Comparative Study ; Journal Article ; Observational Study
Publication Status: ppublish
Abstract
There is a lack of evidence on whether sleeve gastrectomy (SG), which induces fewer nutritional deficiencies than Roux-en-Y gastric bypass (RYGB), also affects fetal growth (FG).
To compare neonatal outcomes after RYGB and SG and to assess the impact of maternal nutritional alterations on FG after both procedures.
University Hospital, France.
Women with singleton pregnancies who had at least 1 nutritional evaluation in our institution between 2004 and 2017 were included. FG was assessed with birth weight (BW) and BW-Z score (adjusted for sex and term), and maternal nutritional deficiencies were defined according to standard and pregnancy-specific norms.
During the study period 123 pregnancies were included, 77 after RYGB and 46 after SG. Weight loss was higher after RYGB than after SG (45.6 ± 12.4 versus 39.5 ± 13.7 kg, P = .02), but mean weight before pregnancy and weight gain during pregnancy were similar. Mean BW (3026 ± 677 versus 3162 ± 712 g), mean BW Z-score and incidence of small for gestational age (24% versus 19%) were not significantly different after RYGB and SG. Mean number of nutritional deficiencies during the second trimester was similar (2.2 ± 1.5 versus 2.1 ± 1.2 with specific norms), but the affected parameters differed between procedures. Urinary urea (R = .285, P = .04) was positively correlated to BW Z-score after both procedures. In contrast, serum iron parameters were negatively associated to BW Z-score.
FG restriction occurs after both SG and RYGB. FG after bariatric surgery is positively associated with protein supply and negatively correlated with maternal iron status.
Keywords
Adult, Bariatric Surgery/adverse effects, Dietary Supplements, Female, Fetal Development/physiology, Fetal Macrosomia/etiology, Gastrectomy/adverse effects, Gastric Bypass/adverse effects, Gestational Weight Gain/physiology, Humans, Infant, Small for Gestational Age, Iron/metabolism, Malnutrition/etiology, Malnutrition/physiopathology, Nutritional Status/physiology, Obesity, Morbid/physiopathology, Obesity, Morbid/surgery, Postoperative Complications/etiology, Postoperative Complications/physiopathology, Pregnancy, Pregnancy Complications/physiopathology, Pregnancy Complications/surgery, Pregnancy Outcome, Pregnancy Trimester, First, Pregnancy Trimester, Second, Prenatal Care, Prenatal Nutritional Physiological Phenomena/physiology, Prospective Studies, Proteins/metabolism, Retrospective Studies, Weight Loss/physiology, Bariatric surgery, Fetal growth, Gastric bypass, Nutritional status, Sleeve gastrectomy
Pubmed
Web of science
Create date
13/12/2021 13:18
Last modification date
14/12/2021 6:33
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