A Light Touch on Sociability.
Details
Serval ID
serval:BIB_6CDA0B3E3F97
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
A Light Touch on Sociability.
Journal
Cell
ISSN
1097-4172 (Electronic)
ISSN-L
0092-8674
Publication state
Published
Issued date
08/08/2019
Peer-reviewed
Oui
Volume
178
Number
4
Pages
769-771
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Comment
Publication Status: ppublish
Publication Status: ppublish
Abstract
Autism spectrum disorder (ASD) is prevalent, complex, and heterogeneous, and currently there is no cure. Identifying shared mechanisms across the ASD spectrum is of utmost importance for therapeutic intervention. Orefice et al. show that tackling the GABA <sub>A</sub> receptor pathway in the peripheral somatosensory system in various ASD mouse models rescues core ASD-like phenotypes.
Keywords
Animals, Autism Spectrum Disorder, Interneurons, Mice, Phenotype, Receptors, GABA-A
Pubmed
Web of science
Create date
16/08/2019 20:13
Last modification date
03/05/2020 6:02