Violent behaviour in early psychosis patients: Can we identify clinical risk profiles?

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Version: Author's accepted manuscript
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Serval ID
serval:BIB_6C8712B606E5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Violent behaviour in early psychosis patients: Can we identify clinical risk profiles?
Journal
Early intervention in psychiatry
Author(s)
Moulin V., Palix J., Golay P., Dumais A., Gholamrezaee M.M., Azzola A., Baumann P.S., Alameda L., Conus P.
ISSN
1751-7893 (Electronic)
ISSN-L
1751-7885
Publication state
Published
Issued date
06/2019
Peer-reviewed
Oui
Volume
13
Number
3
Pages
517-524
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
The objective of this study is to explore, within a sample of early psychosis patients (EPP), if subgroups regarding rate of violent behaviour (VB) against others can be identified on the basis of dynamic risk factors (treatment modifiable characteristics).
In a sample of 265 EPP, treated at the Treatment and Early Intervention in Psychosis Program in Lausanne, we conducted a latent-class analysis on the basis of the main dynamic VB risk factors (substance use disorder [SUD], positive symptoms, insight, and impulsivity). VB were restricted to "serious violence" and were assessed through patients self-report, interview with relatives or forensic services and with a standardized instrument.
The analysis confirmed the heterogeneity of the sample regarding rate of VB. Patients could be stratified within 4 subgroups, 3 of which were at increased risk of VB. The two groups with the highest rates of VB displayed specific clinical profiles. The first one was characterized by high levels of impulsivity, hostility, positive symptoms and SUD, and the second, by low level of insight and low social functioning. These patterns suggest that significant difficulties in social interaction may contribute to the emergence of aggressive reactions against others.
Identification of EPP at increased risk of VB seems possible on the basis of dynamic risk factors. If confirmed prospectively, this could pave the way to the development of preventive strategies and specific interventions.
Keywords
Adolescent, Adult, Female, Humans, Impulsive Behavior, Male, Psychotic Disorders/complications, Psychotic Disorders/psychology, Risk Factors, Social Adjustment, Substance-Related Disorders/complications, Violence/psychology, Young Adult, early psychosis, impulsivity, schizophrenia, violent behaviour
Pubmed
Web of science
Create date
29/11/2017 8:35
Last modification date
08/09/2020 6:09
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