Cost-effectiveness of antihypertensive treatment in patients 80 years of age or older in Switzerland: an analysis of the HYVET study from a Swiss perspective.

Details

Serval ID
serval:BIB_6C76A72B23AA
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cost-effectiveness of antihypertensive treatment in patients 80 years of age or older in Switzerland: an analysis of the HYVET study from a Swiss perspective.
Journal
Journal of Human Hypertension
Author(s)
Szucs T.D., Waeber B., Tomonaga Y.
ISSN
1476-5527[electronic], 0950-9240[linking]
Publication state
Published
Issued date
06/2010
Volume
24
Number
2
Pages
117-123
Language
english
Abstract
This analysis shows the economic benefit of antihypertensive treatment in patients 80 years of age or older from the perspective of the Swiss healthcare system. The cost-effectiveness analysis of antihypertensive treatment in the elderly was carried out applying the results of the Hypertension in the Very Elderly Trial study to the Swiss healthcare system. The analysis shows that hypertension treatment provides, compared with placebo, an additional life expectancy of 0.0457 years per patient, over a follow-up period of 2 years. The medication cost was covered by the reduction of costs related to the treatment of strokes, myocardial infarctions and heart failure: the total cost per patient in the active group resulted in a dominant strategy of savings compared with the placebo group. Sensitivity analysis yielded a stable estimate after varying the costs of medication, stroke, myocardial infarction, heart failure and life expectancy, confirming the robustness of these results. Moreover, considering that antihypertensive treatment also positively affects the incidence of dementia, those net benefits might even be underestimated.
Keywords
Age Factors, Aged, 80 and over, Antihypertensive Agents/economics, Antihypertensive Agents/therapeutic use, Cost Savings, Cost-Benefit Analysis, Double-Blind Method, Drug Costs, Female, Health Care Costs, Health Services for the Aged/economics, Heart Failure/economics, Heart Failure/etiology, Humans, Hypertension/complications, Hypertension/drug therapy, Life Expectancy, Male, Models, Economic, Multicenter Studies as Topic, Myocardial Infarction/economics, Myocardial Infarction/etiology, National Health Programs/economics, Randomized Controlled Trials as Topic, Retrospective Studies, Stroke/economics, Stroke/etiology, Switzerland, Time Factors, Treatment Outcome
Pubmed
Open Access
Yes
Create date
15/12/2009 19:00
Last modification date
21/08/2019 5:33
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