Incidence and Risk Factors for Deep Vein Thrombosis after Radiofrequency and Laser Ablation of the Lower Extremity Veins.

Details

Serval ID
serval:BIB_6C6C85DE4B74
Type
Article: article from journal or magazin.
Collection
Publications
Title
Incidence and Risk Factors for Deep Vein Thrombosis after Radiofrequency and Laser Ablation of the Lower Extremity Veins.
Journal
Annals of vascular surgery
Author(s)
Itoga N.K., Rothenberg K.A., Deslarzes-Dubuis C., George E.L., Chandra V., Harris E.J.
ISSN
1615-5947 (Electronic)
ISSN-L
0890-5096
Publication state
Published
Issued date
01/2020
Peer-reviewed
Oui
Volume
62
Pages
45-50.e2
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Abstract
The rates of thromboembolic complications such as deep vein thrombosis (DVT) after venous ablation procedures for symptomatic superficial venous insufficiency are controversial. We sought to describe the risk factors for and incidence of DVT after radiofrequency ablation (RFA) and laser ablation (LA).
We queried the Truven Health Marketscan Database from 2007-16 for patients who underwent RFA or LA and had a follow-up duplex ultrasound within 30 days of the ablation procedure. The primary outcome was DVT at 7 and 30 days identified by International Classification of Diseases-9 and International Classification of Diseases-10 codes. Multivariable regression was used to evaluate the patient and procedural variables associated with a DVT at 30 days, expressed as odds ratios (ORs) with a 95% confidence interval (95% CI). Patients and procedures with a previous DVT diagnosis were excluded.
A total of 256,999 patients underwent 433,286 ablation procedures: 192,195 (44.4%) RFA and 241,091 LA. Of these, 8,203 (1.9%) had a newly diagnosed DVT within 7 days and 13,347 (3.1%) within 30 days of the procedure. The incidence of DVT decreased over the study period. LA (2.8%) demonstrated a lower incidence of DVT at 30 days compared with RFA (3.4%), P < 0.001. On multivariable regression, LA (OR, 0.82; 95% CI 0.80-0.85) was again associated with a decreased risk for 30-day DVT, as was female gender (OR, 0.74; 95% CI, 0.71-0.77), and sclerotherapy performed on the same day (OR, 0.91; 95% CI, 0.85-0.98). A diagnosis of peripheral artery disease (OR, 1.23; 95% CI, 1.16-1.31) and concomitant stab phlebectomy (OR, 1.43; 95% CI, 1.37-1.49) was associated with an increased risk of DVT within 30 days.
The incidence of newly diagnosed DVT within 30 days of an ablation procedure was 3.2%. The risk for DVT decreased in recent years, and LA was associated with an 18% decreased risk compared with RFA.
Keywords
Adult, Databases, Factual, Female, Humans, Incidence, Laser Therapy/adverse effects, Lower Extremity/blood supply, Male, Middle Aged, Peripheral Arterial Disease/epidemiology, Peripheral Arterial Disease/surgery, Radiofrequency Ablation/adverse effects, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome, United States/epidemiology, Venous Thrombosis/diagnostic imaging, Venous Thrombosis/etiology
Pubmed
Web of science
Open Access
Yes
Create date
09/12/2020 15:44
Last modification date
10/12/2020 6:26
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