An 80-year old American patient was found wandering in a mountain village of Switzerland, with an anterograde, prospective, retrograde, dyschronologic amnesic syndrome without confabulation, paramnesia or false recognitions, disoriented, slightly confused, with no focal sensory, motor, ataxic or visual field deficit, with a mild dysexecutive syndrome. The MR imaging showed an acute thalamo-polar artery infarct. A dysconnection of the mamillo-othalamic and thalamo-temporal pathways is felt at the origin of the amnesic syndrome. A brief review of the other presentation of this chamelon syndrome is presented, together the main etiologies at its origin.