A depauperate immune repertoire precedes evolution of sociality in bees.

Details

Ressource 1Download: genomebiol2.pdf (2517.60 [Ko])
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_6C340359CE44
Type
Article: article from journal or magazin.
Publication sub-type
Minutes: analyse of a published work.
Collection
Publications
Institution
Title
A depauperate immune repertoire precedes evolution of sociality in bees.
Journal
Genome Biology
Author(s)
Barribeau S.M., Sadd B.M., du Plessis L., Brown M.J., Buechel S.D., Cappelle K., Carolan J.C., Christiaens O., Colgan T.J., Erler S., Evans J., Helbing S., Karaus E., Lattorff H.M., Marxer M., Meeus I., Näpflin K., Niu J., Schmid-Hempel R., Smagghe G., Waterhouse R.M., Yu N., Zdobnov E.M., Schmid-Hempel P.
ISSN
1474-760X (Electronic)
ISSN-L
1474-7596
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
16
Pages
83
Language
english
Abstract
BACKGROUND: Sociality has many rewards, but can also be dangerous, as high population density and low genetic diversity, common in social insects, is ideal for parasite transmission. Despite this risk, honeybees and other sequenced social insects have far fewer canonical immune genes relative to solitary insects. Social protection from infection, including behavioral responses, may explain this depauperate immune repertoire. Here, based on full genome sequences, we describe the immune repertoire of two ecologically and commercially important bumblebee species that diverged approximately 18 million years ago, the North American Bombus impatiens and European Bombus terrestris.
RESULTS: We find that the immune systems of these bumblebees, two species of honeybee, and a solitary leafcutting bee, are strikingly similar. Transcriptional assays confirm the expression of many of these genes in an immunological context and more strongly in young queens than males, affirming Bateman's principle of greater investment in female immunity. We find evidence of positive selection in genes encoding antiviral responses, components of the Toll and JAK/STAT pathways, and serine protease inhibitors in both social and solitary bees. Finally, we detect many genes across pathways that differ in selection between bumblebees and honeybees, or between the social and solitary clades.
CONCLUSIONS: The similarity in immune complement across a gradient of sociality suggests that a reduced immune repertoire predates the evolution of sociality in bees. The differences in selection on immune genes likely reflect divergent pressures exerted by parasites across social contexts.
Keywords
Animals, Bees/classification, Bees/genetics, Behavior, Animal, Evolution, Molecular, Female, Gene Expression Regulation, Genes, Insect, Genetic Variation, Male, Selection, Genetic, Social Behavior
Pubmed
Open Access
Yes
Create date
04/03/2016 19:46
Last modification date
04/01/2020 7:17
Usage data