Spirometry and provocation tests for vocal fold dysfunction diagnosis: a retrospective case series.

Details

Serval ID
serval:BIB_6BFD1AD18183
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Spirometry and provocation tests for vocal fold dysfunction diagnosis: a retrospective case series.
Journal
Swiss medical weekly
Author(s)
Taramarcaz P., Seebach J.D., Motteli L., Benaïm C., Schwitzguebel A.J.
ISSN
1424-3997 (Electronic)
ISSN-L
0036-7672
Publication state
Published
Issued date
03/12/2018
Peer-reviewed
Oui
Volume
148
Pages
w14692
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Vocal cord dysfunction (VCD) is characterised by paradoxical inspiratory laryngeal motion and is often misdiagnosed as asthma. Definitive diagnosis of VCD is difficult, because laryngoscopy is positive only during symptomatic episodes or upon provocation with exercise or inhaled irritants. The aims of the study were to better characterise the symptomatology of patients with VCD and to evaluate the potential usefulness of less-invasive diagnostic tools, namely provocation tests and spirometry.
Retrospective case series of 84 patients with a typical clinical history of VCD, in whom at least one of the three following diagnostic tests were performed: laryngoscopy, provocation testing, or spirometry.
The mean age of the patients was 51 years and 74% were women. The principal comorbidities were rhinosinusitis (60%), gastro-oesophageal reflux disease (56%) and atopy (54%). Diagnosis of VCD was confirmed in 73/84 cases (87%), by laryngoscopy (8%), spirometry (84%) and/or provocation tests (68%).
VCD remains an underdiagnosed condition. A negative finding on laryngoscopy can lead to false negative diagnosis if it is done when the patient is asymptomatic. Here we show that a clinical suspicion of VCD, evoked by medical history, can be confirmed in many cases by less invasive diagnostic tools such as spirometry and provocation tests. Future well-conducted prospective case-control studies are needed to draw firmer conclusions and to improve the diagnostic accuracy of this condition. &nbsp.
Keywords
Asthma/diagnosis, Bronchial Provocation Tests/methods, Diagnosis, Differential, Diagnostic Errors, Female, Humans, Laryngoscopy/methods, Male, Middle Aged, Retrospective Studies, Spirometry/methods, Vocal Cord Dysfunction/diagnosis
Pubmed
Create date
17/02/2019 15:22
Last modification date
20/08/2019 14:26
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