Pancytopénie avec anémie hémolytique et schizocytes: une approche pragmatique [Pancytopenia, Hemolytic Anemia and Schizocytes: a Pragmatic Approach].

Details

Serval ID
serval:BIB_6BD7C17A133D
Type
Article: article from journal or magazin.
Collection
Publications
Title
Pancytopénie avec anémie hémolytique et schizocytes: une approche pragmatique [Pancytopenia, Hemolytic Anemia and Schizocytes: a Pragmatic Approach].
Journal
Praxis
Author(s)
Gökok N., Stalder G., Alberio L., Lamy O., Schwotzer N.
ISSN
1661-8157 (Print)
ISSN-L
1661-8157
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
104
Number
14
Pages
751-754
Language
french
Notes
Publication types: Case Reports ; English Abstract ; Journal Article ; Review
Publication Status: ppublish
Abstract
A 58 year old woman presents with a progressive fatigue and dyspnea associated with paresthesia. Laboratory tests show pancytopenia with hypersegmented neutrophiles, macrocytic hyporegenerative anemia and arguments for hemolysis, in particular highly increased LDH. This constellation strongly suggests vitamin B12 deficiency, which was confirmed with an undetectable cobalamine concentration in the blood of our patient. The etiologic work up shows the presence of anti-parietal cells antibodies at a titer of 1/640, diagnostic of Biermer anemia.
Keywords
Anemia, Hemolytic/blood, Anemia, Hemolytic/etiology, Diagnosis, Differential, Erythrocytes, Abnormal/pathology, Female, Humans, Middle Aged, Pancytopenia/blood, Pancytopenia/etiology, Vitamin B 12 Deficiency/blood, Vitamin B 12 Deficiency/diagnosis
Pubmed
Create date
13/11/2015 11:54
Last modification date
12/09/2022 5:39
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