Transfer of cryopreserved-thawed embryos: the natural cycle versus controlled preparation of the endometrium with gonadotropin-releasing hormone agonist and exogenous estradiol and progesterone (GEEP)
Details
Serval ID
serval:BIB_6BD3D4889E85
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Transfer of cryopreserved-thawed embryos: the natural cycle versus controlled preparation of the endometrium with gonadotropin-releasing hormone agonist and exogenous estradiol and progesterone (GEEP)
Journal
Fertility and Sterility
ISSN
0015-0282
Publication state
Published
Issued date
10/1989
Peer-reviewed
Oui
Volume
52
Number
4
Pages
609-16
Notes
Journal Article --- Old month value: Oct
Abstract
Modeled on our successful experience with oocyte donation, we present a novel, viable approach to cryopreserved-thawed embryo transfers (ETs) in women with recalcitrant ovarian dysfunction: gonadotropin-releasing hormone agonist and exogenous estradiol and progesterone (GEEP). After attainment of ovarian suppression, seven such women received physiological steroidal replacement regimens with cryopreserved-thawed ETs prospectively synchronized with the 4th day of progesterone administration and two conceived. These GEEP cycles and cryopreserved-thawed ETs were prospectively compared with cryopreserved-thawed ETs performed on the 4th day of exposure to progesterone in 20 spontaneous cycles and in 5 oocyte donation-steroidal replacement cycles. Pregnancies occurred after three cryopreserved-thawed ETs in each of these groups. We conclude that GEEP constitutes a successful preparation for cryopreserved-thawed ETs, at the least, in women with ovulatory dysfunction.
Keywords
Adult
*Cryopreservation
*Embryo Transfer
Endometrium/*drug effects
Estradiol/blood/*therapeutic use
Female
Humans
Infertility/therapy
Luteinizing Hormone/blood/urine
*Menstrual Cycle
Pituitary Hormone-Releasing Hormones/*physiology
Pregnancy/blood
Progesterone/blood/*therapeutic use
Pubmed
Web of science
Create date
28/02/2008 12:37
Last modification date
20/08/2019 15:26