Prognostic Role of Pre- and Post-Treatment [18F]FDG PET/CT in Squamous Cell Carcinoma of the Oropharynx in Patients Treated with Chemotherapy and Radiotherapy.
Details
Serval ID
serval:BIB_6B93AE097ED6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Prognostic Role of Pre- and Post-Treatment [18F]FDG PET/CT in Squamous Cell Carcinoma of the Oropharynx in Patients Treated with Chemotherapy and Radiotherapy.
Journal
Medical sciences
ISSN
2076-3271 (Electronic)
ISSN-L
2076-3271
Publication state
Published
Issued date
29/07/2024
Peer-reviewed
Oui
Volume
12
Number
3
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Abstract
The prognostic role of imaging with [18F]fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) in oropharynx cancer (OPC) has been demonstrated in the past. The aim of this study was to assess the prognostic impact of both baseline and post-treatment PET/CT in patients with OPC and treated with chemo- and/or radiotherapy.
The PET/CT parameters of scans performed before and after therapy were collected and analyzed to find significant prognosticators for progression-free survival (PFS) and overall survival (OS). Human papillomavirus (HPV) infection's influence on the prognosis was also taken into account.
A total of 66 patients were included in the study. The staging volumetric parameters of PET/CT were significant prognosticators for OS, while the same parameters were affordable predictors for PFS at the restaging evaluation. No significant correlations between HPV infection and PET/CT parameters were reported.
The prognostic role of volumetric [18F]FDG PET/CT parameters in patients with OPC was reported.
The PET/CT parameters of scans performed before and after therapy were collected and analyzed to find significant prognosticators for progression-free survival (PFS) and overall survival (OS). Human papillomavirus (HPV) infection's influence on the prognosis was also taken into account.
A total of 66 patients were included in the study. The staging volumetric parameters of PET/CT were significant prognosticators for OS, while the same parameters were affordable predictors for PFS at the restaging evaluation. No significant correlations between HPV infection and PET/CT parameters were reported.
The prognostic role of volumetric [18F]FDG PET/CT parameters in patients with OPC was reported.
Keywords
Humans, Fluorodeoxyglucose F18/therapeutic use, Positron Emission Tomography Computed Tomography, Male, Female, Middle Aged, Oropharyngeal Neoplasms/diagnostic imaging, Oropharyngeal Neoplasms/radiotherapy, Oropharyngeal Neoplasms/therapy, Prognosis, Aged, Adult, Carcinoma, Squamous Cell/diagnostic imaging, Carcinoma, Squamous Cell/therapy, Radiopharmaceuticals/therapeutic use, Chemoradiotherapy, Aged, 80 and over, Retrospective Studies, Papillomavirus Infections/complications, HPV, PET/CT, SCC, [18]F-FDG, head and neck, oropharynx, positron emission tomography, squamous cell carcinoma
Pubmed
Web of science
Open Access
Yes
Create date
30/08/2024 15:14
Last modification date
31/10/2024 7:13
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