Elements of olfactory reception in adult Drosophila melanogaster.

Details

Serval ID
serval:BIB_6A2A0EE10329
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Elements of olfactory reception in adult Drosophila melanogaster.
Journal
Anatomical Record
Author(s)
Martin F., Boto T., Gomez-Diaz C., Alcorta E.
ISSN
1932-8494 (Electronic)
ISSN-L
1932-8486
Publication state
Published
Issued date
2013
Volume
296
Number
9
Pages
1477-1488
Language
english
Abstract
The olfactory system of Drosophila has become an attractive and simple model to investigate olfaction because it follows the same organizational principles of vertebrates, and the results can be directly applied to other insects with economic and sanitary relevance. Here, we review the structural elements of the Drosophila olfactory reception organs at the level of the cells and molecules involved. This article is intended to reflect the structural basis underlying the functional variability of the detection of an olfactory universe composed of thousands of odors. At the genetic level, we further detail the genes and transcription factors (TF) that determine the structural variability. The fly's olfactory receptor organs are the third antennal segments and the maxillary palps, which are covered with sensory hairs called sensilla. These sensilla house the odorant receptor neurons (ORNs) that express one or few odorant receptors in a stereotyped pattern regulated by combinations of TF. Also, perireceptor events, such as odor molecules transport to their receptors, are carried out by odorant binding proteins. In addition, the rapid odorant inactivation to preclude saturation of the system occurs by biotransformation and detoxification enzymes. These additional events take place in the lymph that surrounds the ORNs. We include some data on ionotropic and metabotropic olfactory transduction, although this issue is still under debate in Drosophila.
Keywords
olfactory receptor organs, antenna, maxillary palps, olfactory reception, drosophila, odorant receptors, odorant binding proteins, olfactory transduction
Pubmed
Web of science
Open Access
Yes
Create date
14/11/2013 9:58
Last modification date
20/08/2019 14:24
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