Retinal nerve fiber layer thickness changes after an acute increase in intraocular pressure.

Details

Serval ID
serval:BIB_6A13FF5C9E7D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Retinal nerve fiber layer thickness changes after an acute increase in intraocular pressure.
Journal
Journal of Cataract and Refractive Surgery
Author(s)
Iester M., Tizte P., Mermoud A.
ISSN
0886-3350
Publication state
Published
Issued date
12/2002
Peer-reviewed
Oui
Volume
28
Number
12
Pages
2117-2122
Language
english
Abstract
PURPOSE: To determine whether the increase in intraocular pressure (IOP) for 45 seconds during laser in situ keratomileusis (LASIK) suction can induce a decrease in retinal nerve fiber layer thickness (RNFLT) assessed by a confocal scanning laser polarimeter. SETTING: Jules Gonin Hospital, University of Lausanne, Lausanne, Switzerland. METHODS: Eleven normal volunteers were enrolled in the study. The optic disc of each eye was analyzed by the GDx(R) Nerve Fiber Analyzer (Laser Diagnostic Technologies, Inc.), version 1.0.14. Using the standard circle that appears as a 10-pixel green circle on the GDx display, the system assessed the RNFLT at 1.75 disc diameter from the outer edge of the optic nerve head. To further evaluate the possible retinal nerve fiber layer (RNFL) loss, the 360-degree circumference was divided into 36 segments measuring 10 degrees each and the RNFLT was calculated for each sector. All subjects had a GDx assessment before 100 mm Hg ocular compression of 1 eye for 45 seconds and then 2 minutes and 1 month after compression. RESULTS: Before compression, the mean RNFLT was 69.09 microm +/- 10.96 (SD); it was 69.27 +/- 10.98 microm after 2 minutes and 67.00 +/- 10.58 microm after 1 month. No statistically significant difference was found between the before and after measurements. CONCLUSION: A 45-second acute increase in IOP, such as during LASIK suction, did not decrease the RNFLT in normal eyes.
Keywords
Adult, Diagnostic Techniques, Ophthalmological, Humans, Intraocular Pressure, Keratomileusis, Laser In Situ, Lasers/diagnostic use, Middle Aged, Nerve Fibers/pathology, Ocular Hypertension/complications, Optic Disk/pathology, Optic Nerve Diseases/etiology, Perimetry, Retinal Ganglion Cells/pathology, Suction
Pubmed
Create date
28/01/2008 12:50
Last modification date
20/08/2019 14:24
Usage data