Body surface area and body weight predict total liver volume in Western adults.

Details

Serval ID
serval:BIB_69FF0047156D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Body surface area and body weight predict total liver volume in Western adults.
Journal
Liver Transplantation
Author(s)
Vauthey J.N., Abdalla E.K., Doherty D.A., Gertsch P., Fenstermacher M.J., Loyer E.M., Lerut J., Materne R., Wang X., Encarnacion A., Herron D., Mathey C., Ferrari G., Charnsangavej C., Do K.A., Denys A.
ISSN
1527-6465
Publication state
Published
Issued date
2002
Peer-reviewed
Oui
Volume
8
Number
3
Pages
233-240
Language
english
Notes
Publication types: Journal Article ; Multicenter Study
Abstract
Computed tomography (CT) is used increasingly to measure liver volume in patients undergoing evaluation for transplantation or resection. This study is designed to determine a formula predicting total liver volume (TLV) based on body surface area (BSA) or body weight in Western adults. TLV was measured in 292 patients from four Western centers. Liver volumes were calculated from helical computed tomographic scans obtained for conditions unrelated to the hepatobiliary system. BSA was calculated based on height and weight. Each center used a different established method of three-dimensional volume reconstruction. Using regression analysis, measurements were compared, and formulas correlating BSA or body weight to TLV were established. A linear regression formula to estimate TLV based on BSA was obtained: TLV = -794.41 + 1,267.28 x BSA (square meters; r(2) = 0.46; P <.0001). A formula based on patient weight also was derived: TLV = 191.80 + 18.51 x weight (kilograms; r(2) = 0.49; P <.0001). The newly derived TLV formula based on BSA was compared with previously reported formulas. The application of a formula obtained from healthy Japanese individuals underestimated TLV. Two formulas derived from autopsy data for Western populations were similar to the newly derived BSA formula, with a slight overestimation of TLV. In conclusion, hepatic three-dimensional volume reconstruction based on helical CT predicts TLV based on BSA or body weight. The new formulas derived from this correlation should contribute to the estimation of TLV before liver transplantation or major hepatic resection.
Keywords
Adult, Body Surface Area, Body Weight, Forecasting, Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Liver/anatomy &amp, histology, Liver/radiography, Middle Aged, Models, Anatomic, Organ Size, Regression Analysis, Tomography, X-Ray Computed, Western World
Pubmed
Web of science
Open Access
Yes
Create date
22/02/2008 10:52
Last modification date
20/08/2019 14:24
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