Allergologie-immunologie - Rhinosinusite chronique avec polypes nasaux : quelle est la place des anticorps monoclonaux en 2020 ? [Chronic rhinosinusitis with nasal polyps : is there a place for monoclonal antibodies in 2020 ?]

Details

Serval ID
serval:BIB_6983B434CAF0
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Allergologie-immunologie - Rhinosinusite chronique avec polypes nasaux : quelle est la place des anticorps monoclonaux en 2020 ? [Chronic rhinosinusitis with nasal polyps : is there a place for monoclonal antibodies in 2020 ?]
Journal
Revue medicale suisse
Author(s)
Clottu A., Reinhard A., Comte D.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
13/01/2021
Peer-reviewed
Oui
Volume
17
Number
720-1
Pages
13-17
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
Chronic rhinosinusitis with nasal polyps is a severe form of chronic rhinosinusitis, which has a strong negative impact on quality of life. Rhinoscopy is helpful for diagnosis, and initial management depends on intra-nasal corticosteroids and sometimes short-term oral corticosteroids (1 to 3 weeks). If well-conducted drug therapy fails, surgery is considered. In the event of post-surgery recurrence or in case of concomitant severe asthma, biologic therapies represent an interesting option. These drugs include dupilumab, mepolizumab, benralizumab and omalizumab. The choice of medication depends on the individual patient context, which includes the presence of atopic dermatitis, eosinophilia, or asthma.
Pubmed
Create date
26/01/2021 14:47
Last modification date
27/07/2021 5:37
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