Myasthenia gravis associated with HTLV-I infection and atypical brain lesions.

Details

Serval ID
serval:BIB_696D57CEECAA
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Myasthenia gravis associated with HTLV-I infection and atypical brain lesions.
Journal
Muscle & nerve
Author(s)
Lalive P.H., Allali G., Truffert A.
ISSN
0148-639X (Print)
ISSN-L
0148-639X
Publication state
Published
Issued date
04/2007
Peer-reviewed
Oui
Volume
35
Number
4
Pages
525-528
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Abstract
We report a patient who experienced progressive diplopia and distal weakness of the upper limbs. Magnetic resonance imaging of the brain showed extensive white matter lesions and analysis of cerebrospinal fluid revealed acute human T-lymphotropic virus type I (HTLV-I) infection. Myasthenia gravis (MG) was evidenced by electromyography (EMG) and antibodies against acetylcholine receptor. This unusual case of MG associated with HTLV-I infection and brain-restricted lesions underscores the possible link between viruses and MG pathogenesis.
Keywords
Autoantibodies/blood, Brain/immunology, Brain/pathology, Brain/virology, Cerebrospinal Fluid/virology, Electromyography, Female, HTLV-I Infections/complications, HTLV-I Infections/diagnosis, HTLV-I Infections/physiopathology, Human T-lymphotropic virus 1/isolation & purification, Humans, Magnetic Resonance Imaging, Middle Aged, Muscle Contraction, Muscle, Skeletal/immunology, Muscle, Skeletal/innervation, Muscle, Skeletal/physiopathology, Myasthenia Gravis/diagnosis, Myasthenia Gravis/physiopathology, Myasthenia Gravis/virology, Neuromuscular Junction/immunology, Neuromuscular Junction/physiopathology, Receptors, Nicotinic/immunology
Pubmed
Web of science
Create date
11/08/2023 14:49
Last modification date
13/10/2023 7:59
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