Etude prospective des effets indesirables lors des desensibilisations allergiques. [Prospective study of the undesirable effects of allergic desensitization]

Details

Serval ID
serval:BIB_6927B0C7C888
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Etude prospective des effets indesirables lors des desensibilisations allergiques. [Prospective study of the undesirable effects of allergic desensitization]
Journal
Schweizerische Medizinische Wochenschrift
Author(s)
Badan  M., Fasel-Felley  J., Kolly  M., Frei  P. C., Pecoud  A.
ISSN
0036-7672 (Print)
Publication state
Published
Issued date
02/1986
Volume
116
Number
8
Pages
243-5
Notes
English Abstract
Journal Article --- Old month value: Feb 22
Abstract
Untoward allergic reactions were monitored prospectively in 98 patients undergoing hyposensitization with depot type preparations of house dust mites (42 patients) or grass pollens administered before the pollen season (56 patients). 44% of the patients experienced at least one major local reaction, usually when injected with high doses of allergens. A mild systemic reaction (benign crisis of rhinitis or asthma within 12 hours after the injection) was reported at least once by 9% of the pollen-treated and 52% of the mite-treated patients. A severe systemic reaction, which improved rapidly with adrenaline, was noted in 3% of the pollen-treated and 5% of the mite-treated patients. These data indicate that untoward allergic reactions during hyposensitization are not uncommon, and this type of treatment therefore requires a strict indication.
Keywords
Allergens/immunology Asthma/drug therapy/etiology/immunology Desensitization, Immunologic/*adverse effects Dust Epinephrine/therapeutic use Humans Mites/immunology Pollen/immunology Prospective Studies Rhinitis, Allergic, Seasonal/drug therapy/etiology/immunology
Pubmed
Web of science
Create date
28/01/2008 11:58
Last modification date
20/08/2019 14:24
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