Zika virus: what do we know?

Details

Serval ID
serval:BIB_6648E7957A5F
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Title
Zika virus: what do we know?
Journal
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Author(s)
Musso D., Baud D., Gubler D.J.
ISSN
1469-0691 (Electronic)
ISSN-L
1198-743X
Publication state
Published
Issued date
06/2016
Peer-reviewed
Oui
Volume
22
Number
6
Pages
494-496
Language
english
Notes
Publication types: Editorial
Publication Status: ppublish

Abstract
The global spread of epidemic Zika virus (ZIKV) began in Micronesia in 2007, followed by epidemics in French Polynesia in 2013-14, other South Pacific islands in 2014-15, and the Americas in 2015-16. A dramatic increase in severe congenital malformations (microcephaly) potentially associated with ZIKV in Brazil, combined with the rapid geographical spread, led the World Health Organization to declare ZIKV epidemic a Public Health Emergency of International Concern. Although ZIKV was first isolated nearly 70 years ago, very little is known about the biology, epidemiology and clinical manifestations because transmission has been sporadic and silent for most of that time. Here we review what is and is not known about ZIKV, with emphasis on the gaps in knowledge about ZIKV and the possible inaccurate assumptions made based on what we know about related viruses.
Keywords
Disease Transmission, Infectious, Guillain-Barre Syndrome/epidemiology, Guillain-Barre Syndrome/etiology, Humans, Microcephaly/epidemiology, Microcephaly/etiology, Zika Virus/isolation & purification, Zika Virus Infection/complications, Zika Virus Infection/diagnosis, Zika Virus Infection/epidemiology, Zika Virus Infection/transmission
Pubmed
Open Access
Yes
Create date
19/04/2016 18:15
Last modification date
22/08/2019 9:31
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