Contemporary prenatal aneuploidy screening practice in Australia: Frequently asked questions in the cell-free DNA era.

Details

Serval ID
serval:BIB_64F866A1D1C2
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Contemporary prenatal aneuploidy screening practice in Australia: Frequently asked questions in the cell-free DNA era.
Journal
The Australian & New Zealand journal of obstetrics & gynaecology
Author(s)
Rieder W., White S., McGillivray G., Hui L.
ISSN
1479-828X (Electronic)
ISSN-L
0004-8666
Publication state
Published
Issued date
08/2018
Peer-reviewed
Oui
Volume
58
Number
4
Pages
397-403
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Cell-free DNA screening has quickly become established in Australia as an accurate - albeit costly - prenatal screening test for trisomy 21, 18 and 13. It is also commonly used for the detection of sex chromosome abnormalities. The increasing number of prenatal screening pathways available to women has increased the complexity of pretest counselling. Concurrent advances in diagnostic testing with the widespread use of chromosomal microarrays create further challenges for the continuing education of clinicians and health consumers. This article aims to answer common clinical questions in this rapidly evolving field and complements the recently updated Royal Australian and New Zealand College of Obstetricians and Gynaecologists Statement on Prenatal Screening for Fetal Chromosome and Genetic Conditions.
Keywords
Australia, Cell-Free Nucleic Acids, Chromosome Disorders/diagnosis, Down Syndrome/diagnosis, Female, Genetic Testing, Humans, Predictive Value of Tests, Pregnancy, Prenatal Diagnosis, Trisomy 13 Syndrome/diagnosis, Trisomy 18 Syndrome/diagnosis, aneuploidy, cell-free DNA, noninvasive prenatal testing, prenatal screening, trisomy 21
Pubmed
Web of science
Open Access
Yes
Create date
23/07/2018 17:54
Last modification date
14/10/2019 6:09
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