Eliminating heterophilic antibody interference for ferritin detection using Olympus F(ab')2 based reagent.

Details

Serval ID
serval:BIB_6482CB5D4F40
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Eliminating heterophilic antibody interference for ferritin detection using Olympus F(ab')2 based reagent.
Journal
Clinical Laboratory
Author(s)
Grouzmann E., Dayer N., Bain C., Neville C.M., McCusker M.D., Wang R.Y.
ISSN
1433-6510
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
54
Number
9-10
Pages
355-357
Language
english
Abstract
Interferences with the Olympus immunoturbidimetric assay for ferritin have been reported because the antibodies used in the immunoassay are derived from rabbits. Rabbits are familiar pets known to be a risk factor for developing heterophilic (or interfering) antibodies. This report shows how the current Olympus Ferritin assay has been improved to eliminate the interference from heterophilic antibodies.
Keywords
Animals, Antibodies, Heterophile/immunology, Antibody Specificity, False Positive Reactions, Ferritins/blood, Ferritins/immunology, Humans, Immunoassay/instrumentation, Immunoassay/methods, Immunoglobulin Fab Fragments/immunology, Nephelometry and Turbidimetry/instrumentation, Nephelometry and Turbidimetry/methods, Rabbits, Sensitivity and Specificity
Pubmed
Web of science
Create date
03/10/2009 8:23
Last modification date
20/08/2019 14:20
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