Echo-time independent signal modulations for strongly coupled systems in triple echo localization schemes: an extension of S-PRESS editing.

Details

Serval ID
serval:BIB_638B1BDAB21E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Echo-time independent signal modulations for strongly coupled systems in triple echo localization schemes: an extension of S-PRESS editing.
Journal
Journal of Magnetic Resonance
Author(s)
Kickler N., Gambarota G., Mekle R., Gruetter R., Mulkern R.
ISSN
1096-0856[electronic], 1090-7807[linking]
Publication state
Published
Issued date
2010
Volume
203
Number
1
Pages
108-112
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
The double spin-echo point resolved spectroscopy sequence (PRESS) is a widely used method and standard in clinical MR spectroscopy. Existence of important J-modulations at constant echo times, depending on the temporal delays between the rf-pulses, have been demonstrated recently for strongly coupled spin systems and were exploited for difference editing, removing singlets from the spectrum (strong-coupling PRESS, S-PRESS). A drawback of this method for in vivo applications is that large signal modulations needed for difference editing occur only at relatively long echo times. In this work we demonstrate that, by simply adding a third refocusing pulse (3S-PRESS), difference editing becomes possible at substantially shorter echo times while, as applied to citrate, more favorable lineshapes can be obtained. For the example of an AB system an analytical description of the MR signal, obtained with this triple refocusing sequence (3S-PRESS), is provided.
Keywords
Algorithms, Calibration, Citrates/chemistry, Electromagnetic Fields, Humans, Male, Nuclear Magnetic Resonance, Biomolecular/methods, Prostate/chemistry
Pubmed
Web of science
Create date
04/08/2010 15:28
Last modification date
20/08/2019 14:20
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