The history and role of long duration stimulation in fMRI.

Details

Serval ID
serval:BIB_636B1C0B8006
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The history and role of long duration stimulation in fMRI.
Journal
Neuroimage
Author(s)
Krueger G., Granziera C.
ISSN
1095-9572 (Electronic)
ISSN-L
1053-8119
Publication state
Published
Issued date
2012
Volume
62
Number
2
Pages
1051-1055
Language
english
Notes
Publication types: Historical Article ; Journal Article ; Review
Publication Status: ppublish
Abstract
During the past 20 years, BOLD fMRI has developed towards a central and fundamental tool in neuroscience. It has been shown that the BOLD response provides an indicator of neuronal activity in the brain. Consequently, for an accurate interpretation of findings in BOLD MRI experiments and to draw meaningful conclusions about the temporal evolution of neural events, a deep understanding of the nature of the BOLD contrast has become of essential importance. Since the dynamics of the major direct determinants of the BOLD signal (CBF, CBV and CMRO(2)) range between seconds and minutes, long duration stimulation was an early key strategy needed to study and understand the BOLD characteristics. This paper summarizes and discusses the thoughts and rationales of the long duration stimulation studies.
Keywords
Animals, Brain/blood supply, Brain/physiology, Brain Mapping/history, Brain Mapping/methods, Cerebrovascular Circulation/physiology, History, 20th Century, History, 21st Century, Humans, Magnetic Resonance Imaging/history, Magnetic Resonance Imaging/methods, Oxygen/blood
Pubmed
Web of science
Create date
10/03/2012 19:51
Last modification date
20/08/2019 14:20
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