Cell therapies for skin regeneration: an overview of 40 years of experience in burn units.

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Ressource 1Download: 2019_Abdel_Sayed.pdf (963.98 [Ko])
State: Public
Version: author
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_63158D24E889
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Cell therapies for skin regeneration: an overview of 40 years of experience in burn units.
Journal
Swiss medical weekly
Author(s)
Abdel-Sayed P., Michetti M., Scaletta C., Flahaut M., Hirt-Burri N., de Buys Roessingh A., Raffoul W., Applegate L.A.
ISSN
1424-3997 (Electronic)
ISSN-L
0036-7672
Publication state
Published
Issued date
06/05/2019
Peer-reviewed
Oui
Volume
149
Pages
w20079
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Abstract
The earliest attempts at cell therapy can be attributed to Charles-Edward Brown-Séquard (1817–1894), who sought to treat senescence and aging by injecting animal gonad shreds into his contemporaries, a practice that was widespread in late 19th century. Since then, advances in science have enabled the development of biological substitutes to restore the function of various tissues. Skin was one of the first tissues to be regenerated. For severe burns, patient survival depends on the restoration of skin function as a barrier against pathogens and control of body temperature and fluid loss. We aim here to overview the different cell therapy techniques implemented at the University Hospital of Lausanne (CHUV), one of the two Swiss national centres of highly specialised medicine for burn care. In particular, we will describe the specific indications for each of the different therapies as well as future perspectives.
Keywords
Burn Units, Burns/therapy, Cell- and Tissue-Based Therapy/methods, Hospitals, University, Humans, Regeneration, Skin/physiopathology, Skin Transplantation/methods, Switzerland
Pubmed
Web of science
Open Access
Yes
Create date
25/05/2019 13:15
Last modification date
06/09/2020 6:23
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