Gliomas in children: a review

Details

Serval ID
serval:BIB_630AD9991D5E
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Gliomas in children: a review
Journal
Child's Nervous System
Author(s)
Rilliet  B., Vernet  O.
ISSN
0256-7040 (Print)
Publication state
Published
Issued date
11/2000
Volume
16
Number
10-11
Pages
735-41
Notes
Journal Article
Review --- Old month value: Nov
Abstract
The management and prognosis of gliomas are significantly different in children and in adults. Fortunately, the proportion of gliomas that are malignant is smaller in children than in the adult population. The different types of gliomas encountered in the pediatric population are reviewed, taking account of the most recent contributions on this subject. The importance of considering both localization and histological classification for better definition of the prognostic factors of each subgroup is emphasized. A brief review of the possible causes of gliomas is presented. Unfortunately, the information obtained by molecular and genetic study of these tumors has still not resulted in anything that can help the children suffering from gliomas in a concrete way. Surgery, with all its recent refinements, remains the best treatment for the majority of benign gliomas providing they can be removed without unacceptable sequelae. The role of chemotherapy has emerged recently for the treatment of nonresectable low-grade gliomas, such as hypothalamic-chiasmatic tumors, especially for infants, in whom the adverse effects of radiotherapy can be severe and irreversible. On the eve of the new millennium, there is renewed hope that the problem of malignant gliomas will be solved in the not-too-distant future.
Keywords
Brain Neoplasms/diagnosis/mortality/*surgery Child Glioma/diagnosis/mortality/*surgery Humans Prognosis Survival Rate
Pubmed
Web of science
Create date
25/01/2008 13:13
Last modification date
20/08/2019 14:19
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