Les tests génétiques peuvent-ils être utiles pour la prévention cardiovasculaire? [Are genetic tests useful for cardiovascular prevention?].

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Version: author
Serval ID
serval:BIB_62E7AC450B47
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Les tests génétiques peuvent-ils être utiles pour la prévention cardiovasculaire? [Are genetic tests useful for cardiovascular prevention?].
Journal
Revue médicale suisse
Author(s)
Bochud Murielle, Fellmann Florence, Guessous Idris
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2012
Volume
8
Number
331
Pages
519-20, 522-4
Language
french
Abstract
Recent progresses in genetics have opened new avenues to further our understanding of the pathophysiological mechanisms underlying cardiovascular disease, raising, new expectations in the field of personalized medicine. Genetic tests may have a high predictive value for rare monogenic diseases. The situation is very different for common polygenic diseases, such as myocardial infarction, type 2 diabetes or stroke. The results from recent genome-wide association studies have provided useful information for research, but have not yet been proven to be clinically useful. It is therefore currently not recommended to conducted genetic testing to guide cardiovascular prevention neither in clinical nor in public health settings.
Keywords
Cardiovascular Diseases/diagnosis, Cardiovascular Diseases/genetics, Chemoprevention, Genetic Testing, Humans, Risk Factors
Pubmed
Create date
31/05/2012 19:36
Last modification date
20/08/2019 15:19
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