Gonadotrophin replacement for induction of fertility in hypogonadal men.

Details

Serval ID
serval:BIB_629AC81064AE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Gonadotrophin replacement for induction of fertility in hypogonadal men.
Journal
Best Practice and Research. Clinical Endocrinology and Metabolism
Author(s)
Dwyer A.A., Raivio T., Pitteloud N.
ISSN
1878-1594 (Electronic)
ISSN-L
1521-690X
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
29
Number
1
Pages
91-103
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Congenital hypogonadotrophic hypogonadism (CHH) is a rare form of infertility caused by deficient secretion or action of gonadotrophin-releasing hormone. There is no consensus regarding the optimal approach to fertility treatment in CHH men. In most cases, appropriate hormonal treatment with human chorionic gonadotrophin with or without follicle stimulating hormone will induce testicular development, spermatogenesis and fertility. Recent studies have examined sequential treatment with FSH pre-treatment to optimize fertility outcomes in severely affected CHH patients. This paper reviews historical and recent literature to summarize the current evidence on therapeutic approaches for CHH men seeking fertility.
Keywords
Follicle Stimulating Hormone/therapeutic use, Gonadotropin-Releasing Hormone/deficiency, Humans, Hypogonadism/complications, Hypogonadism/congenital, Infertility, Male/drug therapy, Infertility, Male/etiology, Male, Treatment Outcome
Pubmed
Web of science
Create date
19/03/2015 21:37
Last modification date
20/08/2019 15:19
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